Destroy Me may refer to:
- Destroy Me, 2012 sequel novel to Shatter Me, by Tahereh Mafi
- "Destroy Me", 2023 song by American musician Rebecca Black from the album, Let Her Burn
- "Destroy Me", 2025 song by American musician 2hollis from the album, Star
- "Destroy Me" (President song), 2025 single by English metal band President
See also
- Destroy Me, Lover, 1993 studio album by American noise rock and Industrial music band Pain Teens
- "Don't Destroy Me", 1959 rockabilly song written by Barry Mann and Joe Sharpiro and recorded by Billy "Crash" Craddock
- Use Once and Destroy Me, 2003 concert tour DVD by American rock band Mondo Generator