EPO or epo may refer to:
Organisations
Science and technology
- Education and public outreach
- Electrolytic plasma oxidation, a metal surface treatment process
- Emergency power off
- Erythropoietin, a red blood cell production hormone and performance-enhancing drug
- Evening primrose oil
- Eosinophil peroxidase, an enzyme
Other uses
- Emergency Powers Order, per the Irish Emergency Powers Act 1939
- Emergency protection order, under the UK's Children Act 1989
- Epo (musician), Indonesian hip hop musician
- Esperanto (ISO 639-2 code), a constructed language
- European Payment Order, a debt-collecting system in the EU
- Exclusive provider organization, in US health insurance