Ryukyu may refer to:
- Ryukyu Islands, a volcanic arc archipelago
- Ryukyuan languages
- Ryukyuan people
- Kingdom of Ryukyu (1429–1879)
- Ryukyu Broadcasting Corporation, a radio and television broadcaster in Okinawa Prefecture, Japan
- Ryukyu Asahi Broadcasting, a television station in Okinawa Prefecture, Japan
- University of the Ryukyus, a university in Okinawa Prefecture, Japan
- Ryuko Tatsuma, a character in the animanga series My Hero Academia