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This is a list of foreign ministers of Panama from 1945 to the present day.
- 1941–1944: Octavio Fábrega López
- 1945–1947: Horacio F. Alfaro
- 1947–1948: Mario de Diego
- 1948............ Ernesto Jaén Guardia
- 1948–1949: Ignacio Carlos Molino de Diego
- 1949............ Samuel Lewis Arango
- 1949............ Guillermo Méndez Pereira
- 1949–1951: Carlos N. Brin
- 1951–1952: Ignacio Carlos Molino de Diego
- 1952–1955: José Ramón Guizado
- 1955............ Octavio Fábrega López
- 1955............ Ricardo Arias
- 1955–1956: Alberto A. Boyd
- 1956–1958: Aquilino Boyd
- 1958–1960: Miguel J. Moreno
- 1960–1964: Galileo Solís
- 1964–1968: Fernando Eleta Almarán
- 1968–1969: Carlos Alfredo López Guevara
- 1969............ Nander Antberto Pitty Velásquez
- 1969–1976: Juan Antonio Tack
- 1976–1977: Aquilino Boyd
- 1977–1978: Nicolás González Revilla
- 1978–1981: Carlos Ozores Typaldos
- 1981–1982: Jorge Illueca
- 1982–1983: Juan José Amado
- 1983–1984: Oydén Ortega Durán
- 1984–1985: Fernando Cardoze
- 1985–1988: Jorge Abadía Arias
- 1988–1989: Jorge Eduardo Ritter
- 1989............ Gustavo R. González
- 1989............ Leonardo Kam
- 1989–1993: Julio Linares
- 1993–1994: José Raúl Mulino
- 1994–1996: Gabriel Lewis Galindo
- 1996–1998: Ricardo Alberto Arias
- 1998–1999: Jorge Eduardo Ritter
- 1999–2003: José Miguel Alemán
- 2003–2004: Harmodio Arias Cerjack
- 2004–2009: Samuel Lewis Navarro
- 2009–2011: Juan Carlos Varela
- 2011–2012: Roberto Henríquez
- 2012............ Francisco Álvarez De Soto (acting)
- 2012–2013: Rómulo Roux
- 2013–2014: Fernando Núñez Fábrega
- 2014............ Francisco Álvarez De Soto
- 2014–2019: Isabel Saint Malo
- 2019–2020: Alejandro Ferrer López
- 2020–2022: Erika Mouynes
- 2022–2024: Janaina Tewaney
- 2024–: Javier Martínez-Acha